Letter by Sacha regarding article, "clinical and genetic determinants of torsade de pointes risk".
نویسنده
چکیده
منابع مشابه
Contemporary Reviews in Cardiovascular Medicine Clinical and Genetic Determinants of Torsade de Pointes Risk
Torsade de pointes (TdP) is a stereotyped polymorphic ventricular tachycardia characterized by a cyclic shifting of the QRS axis (twisting around the points of the isoelectric line) preceded by a prolonged QT interval (Figure 1). It is the quintessential arrhythmia of the long-QT syndrome (LQTS), whether congenital or acquired, and results from a complex interplay among structural, metabolic, g...
متن کاملClinical and genetic determinants of torsade de pointes risk.
Torsade de pointes (TdP) is a stereotyped polymorphic ventricular tachycardia characterized by a cyclic shifting of the QRS axis (twisting around the points of the isoelectric line) preceded by a prolonged QT interval (Figure 1). It is the quintessential arrhythmia of the long-QT syndrome (LQTS), whether congenital or acquired, and results from a complex interplay among structural, metabolic, g...
متن کاملSERIOUS ARRHYTHMIA INDUCED BY TERFENADINE-ERYTHROMYCIN INTERACTIONS
Since the introduction of our local manufacturing of terfenadine, we have observed and expressed our concern about a small but increasing number of serious ventricular arrhythmias associated with the use of this non sedating antihistamine. In January 1997 a case of torsade de pointes ventricular tachycardia was detected in a previously healthy woman taking terfenadine with erythromycin. El...
متن کاملمعرفی یک مورد بیمار نجات یافته از مرگ ناگهانی ناشی از سندرم QT طولانی
Çongenital long-QT syndrome (LQTS) is an inherited disorder that presents with syncope, polymorphic ventricular tachycardia, torsade de pointes and sudden death. The incidence rate of LQTS is 1 to 2 per 100000 and mainly involves children and young individuals. Because of familial and genetic underling and predisposing factors for life threatening arrhythmias in patients, diagnosis and treatm...
متن کاملTorsade de pointes: the clinical considerations.
Torsade de pointes is a form of polymorphic ventricular tachycardia occurring in a setting of prolonged QT interval on surface electrocardiogram. Congenital causes of prolonged QT interval occur in individuals with genetic mutations in genes that control expression of potassium and sodium channels and acquired causes are numerous, predominantly drugs causing prolonged QT interval by blockade of...
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ورودعنوان ژورنال:
- Circulation
دوره 126 19 شماره
صفحات -
تاریخ انتشار 2012